Skip to content
Main Street Cannabis Logo & Home button
Shop Med Shop Non-Med Visit Loyalty Events
Shop Med Shop Non-Med Visit Loyalty Events

Main Street Cannabis Co.

Columbus Dispensary

3111 East Main Street, Columbus, Ohio

Monday - Sunday: 10 AM - 8 PM

(614) 670-4384
Shop Med Shop Non-Med
Online Ordering

Online Ordering

On-site ATM

On-site ATM

Accepts Cash

Accepts Cash

Accepts Debit

Accepts Debit

On-site Parking

On-site Parking

ADA Accessible

ADA Accessible

Visit OUR COLUMBUS DISPENSARY

Your Neighborhood Downtown Dispensary

Conveniently located, Main Street Cannabis Co. delivers personalized care and a welcoming environment. Our expert budtenders provide individualized recommendations to ensure you find the right products.

Visit us today and experience why our customers feel like VIPs every time.

Get Directions

Discover Trusted Brands

We proudly feature a curated selection of trusted cannabis brands, discover the best from the brands you know and love.

Shop Med Brands Shop Non-Med Brands
Andshine Logo
Ancient Roots Logo
Butterfly Effect Logo
Beneleaves Logo
Bukceye Relief Logo
Certified Logo
Cresco Logo
Dialed In Gummies Logo
Dixie Gummies Logo
Edens Trees Logo
Farkas Farms Logo
Firelands Scientific Logo
Fuzed Logo
Galenas Logo
Good Green Logo
Gron Logo
Hz Logo
Incredibles Logo
King City Logo
Klutch Logo
Kynd Logo
Meigs County Grown Logo
Moxie Logo
Oregon Green Systems Logo
Paragon Premium Cannabis Logo
Riviera Creek Logo
Rythm Logo
Sauce Logo
Savvy Logo
Smokies Logo
Standard Wellness Logo
The Standard Logo
Timeless Logo
Ub Good Logo
Wellspring Fields Logo

Shop by Category

Find Your Perfect Match

Explore our wide range of cannabis to find the perfect products for your needs.

Shop Med Shop Non-Med

Dispensary Loyalty Program

Loyalty Pays Off

Join our loyalty program and get early access to new products and invited to VIP events.

Join Now Learn More

Columbus Dispensary FAQs

Main Street Cannabis in Columbus offers both non-medical and medical cannabis products. Whether you're a patient looking for relief or a non-medical user seeking a premium experience, our knowledgeable staff is here to assist you.
We accept government-issued photo IDs for age verification, including driver's licenses, state IDs, and passports. Make sure your ID is valid and indicates that you are 21 or older to enter our dispensary.
Our Columbus dispensary is open from 10 AM to 8 PM, seven days a week, making it convenient for you to stop by whether you need to restock or explore new products.
Under Ohio law, adults 21 and older can purchase up to 2.5 ounces of cannabis flower or up to 15 grams of marijuana concentrate per transaction. Please note that these purchase limits are strictly enforced.
Join our dispensary loyalty program and get the best deals in the neighborhood. Loyalty members get access to exclusive deals, early product launches, and special savings opportunities.
Yes, our dispensary is conveniently located about 10 minutes from John Glenn Columbus International Airport, making it easy for travelers to stop by before or after their flights.
We are located approximately 14 minutes from the Nationwide Arena, 19 minutes from Ohio Stadium, and 16 minutes from Lower.com Field, making us a great stop for fans before or after attending a concert or cheering on their favorite Columbus sports teams.
Main Street Cannabis is located around 12 minutes from the Columbus Museum of Art, offering a convenient stop for art enthusiasts looking to explore cannabis culture before or after their museum visit.
We are near several parks, including Franklin Park Conservatory and Botanical Gardens, which is just a short, 10 minute drive away. It's the perfect spot for a relaxing walk or picnic after visiting our dispensary.
If this is your first time visiting a dispensary, welcome to your journey with cannabis. Be sure to bring your state-issued photo ID for age verification (21 and over), and brush up on local Ohio cannabis laws. Under Ohio law, anyone 21 and up can possess and consume marijuana. A person can buy up to 2.5 ounces of the product but cannot possess more than 15 grams of marijuana concentrate at one time.

Whether you're visiting us from Ohio State University, looking through our extensive selection of cannabis strains to help you relax or stay focused, your next stop could be grabbing a coffee at Stauf's Coffee Roasters just a few blocks away. If you’re here for a strain that promotes focus, you can also check out the Columbus Metropolitan Library nearby for a quiet study spot.

As a dispensary near OSU, our experienced budtenders are ready to offer recommendations for students, including the best strains for creativity and productivity.

If you’re interested in experiencing Columbus's arts and culture, the Columbus Museum of Art and COSI are both within easy reach. On weekends, consider visiting the North Market, a bustling space filled with local artisans, food vendors, and live music. If you’re in the mood for nature, take a relaxing walk or have a picnic at Franklin Park Conservatory and Botanical Gardens, perfect after picking up some product from our dispensary.

We are proud to provide excellent customer service and high-quality products to the following communities: Downtown Columbus, Whitehall, Bexley, Gahanna, and Reynoldsburg.

Are you at least 21 years old or a qualified patient?

No, I’m underage